Chromatogram Software For Mac

View, edit, and convert chromatograms. Trim low quality ends automatically.

Program description

DNA Chromatogram Explorer Lite is a Windows Explorer clone dedicated to DNA sequence analysis and manipulation. You can view the chromatograms while browsing through folders using its integrated file explorer. With a single click you can trim the low quality bases at the end of your samples.

Chromatography software is software that collects and analyzes chromatographic results delivered by chromatography detectors. Many chromatography software packages are provided by manufacturers, and many of them only provide a simple interface to acquire data. They also provide different tools to analyze this data. This phase can be done efficiently and easily when you work with a software tool that allows you to set up the criteria for the sequence alignment, as well as editing your template sequence based on the sequencing result you have. Here’s the top 5 essential tools to look for in your sequence alignment software: Efficient Visualization.

The Lite version of Chromatogram Explorer is freeware.

How to use it

Exploring your samples

Start DNA Chromatogram Explorer and navigate to your DNA sample files (chromatograms).

All chromatograms in that folder will be displayed in the right panel (see picture below). SCF and ABI (ABI, AB, AB1, AB!) chromatogram files are supported. Low quality ends are shown in dark gray color. To view non-chromatogram files (FASTA, SEQ, TXT) just double click them.

Converting your samples

Press 'Convert' or 'Convert all' and your file will be saved as SCF or FASTA (as you choose).

Automatic end trimming

With DNA Chromatogram Explorer you can automatically trim low quality ends of all chromatograms in a folder. Please see this short tutorial.

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How to install it

DNA Chromatogram Explorer is delivered in a small package together with other free molecular biology tools.

You don't need administrator rights in order to 'install' this package.

Download the package
Double click it to unpack it
Specify the destination folder (where to unpack it)
Go to the destination folder and double click the program you want to use

Name	Chromatogram Explorer Lite
Version	3.2
Package size	~ 5 MB
Download time	less than 12 seconds (for DSL)

Uninstall

DNA Chromatogram Explorer installs zero files in your system. Therefore, you don't need to uninstall it. To uninstall the DNA Chromatogram Explorer, just delete it.

Portability

This software tool is really small so you can easily copy it on a floppy disk or USB flash stick and take it with you or send it to your colleagues via email.

System requirements

DNA Chromatogram Explorer can run on any version of Windows from Windows 98 to Windows 7 and also on Mac via Parallels or Bootcamp. It does not install additional libraries, updates, DLL, Java or registry keys into your system.

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Feature	Lite	Pro
Display sample's content as you browse through your folders
Highlight low quality regions
Manually trim low quality end
Automatically trim low quality ends (batch)
Convert between miscellaneous formats
View FASTA, SEQ, TXT samples
View SCF, ABI, AB, AB!, AB1 samples
View sample's properties & statistics
View confidence scores
Extract bases from chromatograms (copy to clipboard)
Perform file operations (copy/delete/move samples)
Show all chromatogram files in a folder
Convert all samples in a folder
Double click a file to open it

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Similar bioinformatics tools included in this package

Name	Description
DNA Sequence Assembler	DNA Baser is a tool for DNA sequence assembly, DNA sequence analysis, contig editing, and mutation detection. It also offers a powerful chromatogram viewer/editor.
GBK to FASTA converter	GenBank to FASTA is a freeware program will convert GenBank (gbk) file format to FASTA format.
ABI to FASTA converter	ABI to FASTA Converter is a free tool will convert all (selected) ABI files to FASTA files. All you need to do is to locate your ABI chromatogram files and press the CONVERT button.
Grid cell counter	Gird cell counter will help you to count faster the cells shown on computer's screen by displaying a grid over your image. Freeware.
Convertrix	Convertrix is a molecular biology command line tool for converting between several popular DNA sample formats. It can automatically trim the untrusted regions (low quality bases) at the end of samples.
DNA Counter	DNA Counter shows the proportions between nucleotides in a DNA sequence (GC to AT ratio).
Chromatogram Explorer	DNA Chromatogram Explorer is a Windows Explorer clone dedicated to DNA sequence analysis and manipulation. You can view the chromatograms while browsing through folders using its integrated file explorer. With a single click you can trim the low quality bases at the end of your samples.
Everything to FASTA converter	Everything to Fasta Converter converts the specified samples (SCF, ABI, FASTA, multiFasta, GBK, multiGBK, SEQ, TXT) to FASTA format. Starting with version 3.0 protein FASTA files are also supported.

[Project Page, Support] Skyline is a freely-available, open-source Windows client application for building Selected Reaction Monitoring (SRM) / Multiple Reaction Monitoring (MRM), Parallel Reaction Monitoring (PRM), DIA/SWATH and targeted DDA quantitative methods and analyzing the resulting mass spectrometer data. Its flexible configuration supports All Molecules. It aims to employ cutting-edge technologies for creating and iteratively refining targeted methods for large-scale quantitative mass spectrometry studies in life sciences.

Build Targeted Methods

Use prior knowledge of your proteins and peptides of interest to improve your measurement selectivity and precision.

See Quantitative Results

Learn more about your quantitative measurements through the rich and interactive Skyline graphical data displays.

Store and Share Experiments

Panorama stores the entire Skyline data model, where you and your collaborators can explore it with a web browser.

Build Chromatogram Libraries

Use Panorama to build fully validated chromatogram assay libraries you can use in Skyline for new experiments.

[Project Page, Support] Panorama is a freely-available, open-source targeted proteomics website knowledgebase for sharing experiments and validated assays that integrates into a Skyline proteomics workflow. It can be installed on a local server, or you can request a project on the PanoramaWeb.org server, hosted by the MacCoss Lab at the University of Washington. Access privileges within a project may be customized, allowing you to control fully who has access to data you publish to Panorama.

[Project Page] EncyclopeDIA is an open-source library search engine for DIA data analysis. It searches for peptides using either DDA-based spectrum libraries or DIA-based chromatogram libraries. Walnut, an implementation of PECAN, generates chromatogram libraries from FASTA databases when spectrum libraries are unavailable.

[Project Page] BiblioSpec 2.0 is the open-source spectral library build engine used by Skyline. It supports 18 different peptide search pipelines, and can be run separately from Skyline on Windows and Linux computers. It also supports using spectral libraries for peptide identification of MS/MS scans from DDA data.